| Customization: | Available |
|---|---|
| CAS No.: | 864731-61-3 |
| Formula: | C22H17Cl2F6N3O3 |
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Fluralaner is a systemic isoxazoline-class insecticide and acaricide widely used in veterinary medicine and agriculture due to its broad-spectrum, long-lasting efficacy against ectoparasites. Below are its key applications:
Product: Bravecto® (by Boehringer Ingelheim)
Formulations:
Chewable tablets
Spot-on solutions
Injectable formulations ( Bravecto® 12-week injection)
Target Parasites:
| Parasite Type | Examples | Efficacy Duration |
|---|---|---|
| Fleas | Ctenocephalides felis () | 12 weeks |
| Ticks | Ixodes, Rhipicephalus, Dermacentor | 8-12 weeks |
| Mites | Sarcoptes scabiei () | Single dose effective |
| Lice | Trichodectes canis () | 8 weeks |
Application:
Controls poultry red mites (Dermanyssus gallinae) in chickens.
Used against ticks and lice in cattle and pigs.
Withdrawal Period:
Eggs: ~14 days (varies by country).
Meat: ~28 days (ensure compliance with local regulations).
Fluralaner is also explored in crop protection against:
Spider mites (Tetranychus urticae) in fruits & vegetables.
Thrips and whiteflies in greenhouse crops.
Mode of Action: Disrupts GABA-gated chloride channels (similar to fipronil but with higher safety margins).
Potential use in controlling:
Bed bugs ( Cimex lectularius).
Mosquitoes (/, limited research).
Long-lasting effect: Single dose protects for 8-12 weeks (vs. monthly treatments like fipronil).
Broad-spectrum: Kills fleas, ticks, mites, and lice.
Safety: High margin of safety for mammals (low toxicity to dogs/cats at therapeutic doses).
Not effective against internal parasites (e.g., roundworms, tapeworms).
Environmental concerns: Persistence in manure/water (requires proper disposal).
Resistance risk: Overuse may lead to parasite resistance (monitoring needed).
| Drug | Class | Duration | Spectrum | Safety |
|---|---|---|---|---|
| Fluralaner | Isoxazoline | 8-12 weeks | Fleas, ticks, mites | High (veterinary) |
| Afoxolaner | Isoxazoline | 4 weeks | Fleas, ticks | Moderate |
| Fipronil | Phenylpyrazole | 4 weeks | Fleas, ticks | Lower (neurotoxicity risk) |
| Selamectin | Avermectin | 1 month | Fleas, mites, heartworm | Caution in collies |
Combination products:
Fluralaner + Moxidectin (for heartworm prevention).
Fluralaner + Lufenuron (flea egg control).
Expanding markets:
Emerging demand in Asia & Latin America for pet parasite control.
Potential human use (e.g., scabies treatment under investigation).
Fluralaner is a revolutionary parasiticide in veterinary medicine, offering long-lasting, safe, and broad-spectrum protection. While its primary use is in pets, applications in livestock and agriculture are growing. Future developments may include new formulations and combination therapies to combat resistance.
| Packaging Detail: | For liquid: 200Ltr/drum, 20L/drum, 1L/bottle, 500ml/bottle, 250ml/bottle, 100ml/bottle. For solid: 25 kg/drum, 25kg/bag, 1kg/bag or on the requirement of client. |
| Delivery Detail: | 20-30days |
HANGZHOU TIANLONG BIOTECHNOLOGYCO.,LTD
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