Chemical Intermediate N-Bromosuccinimide 99% CAS 128-08-5

• Customization: Available
• Grade Standard: Medicine Grade, Industrial Grade, Agriculture Grade
• Appearance: Solid
• Model NO.: 99%
• Certification: ISO
• CAS: 128-08-5
• Shelf life: 2 years
• Quality: TOP
• Content: Standard
• Transport Package: Follow Customer′s Request.
• Specification: GB/FAO/SGS
• Trademark: TOP AGRO
• Origin: Zhejiang, China
• HS Code: 2924
• Production Capacity: 1, 000 T/Year

Product Description

 

Product Description

 

Common Name	N-Bromosuccinimide
CAS Number	128-08-5	Molecular Weight	177.984
Density	2.0±0.1 g/cm3	Boiling Point	221.4±23.0 °C at 760 mmHg
Molecular Formula	C4H4BrNO2	Melting Point	175-180 °C (dec.)(lit.)

Chemical & Physical Properties

Density	2.0±0.1 g/cm3
Boiling Point	221.4±23.0 °C at 760 mmHg
Melting Point	175-180 °C (dec.)(lit.)
Molecular Formula	C4H4BrNO2
Molecular Weight	177.984
Flash Point	87.7±22.6 °C
Exact Mass	176.942535
PSA	37.38000
LogP	-0.70
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.606
Stability	Stable. Incompatible with strong oxidizing agents, halogenated hydrocarbons.

 

Packaging & Shipping

 

For liquid	200Ltr/drum, 20L/drum, 1L/bottle, 500ml/bottle, 250ml/bottle, 100ml/bottle.
For solid	25 kg/drum, 25kg/bag, 1kg/bag or on the requirement of client.
Delivery Detail	20-30days

 

Applications

N-Bromosuccinimide (NBS) is a versatile brominating and oxidizing agent widely used in organic synthesis, pharmaceuticals, and material science. Below are its key applications:

 

1. Organic Synthesis 

 Allylic & Benzylic Bromination 

• Selectively brominates alkenes (e.g., cyclohexene → 3-bromocyclohexene) and aromatics under mild conditions.

• Example: Synthesis of brominated terpenes for fragrances.

 Electrophilic Aromatic Substitution 

• Brominates phenols, anilines, and activated rings (e.g., para-bromoaniline production).

 Oxidation Reactions 

• Converts alcohols to aldehydes/ketones (alternative to PCC/Dess-Martin).

• Oxidizes thioethers to sulfoxides (e.g., in drug metabolism studies).

 

2. Pharmaceutical & Agrochemistry

 Drug Intermediate Synthesis

• Key step in producing antibiotics (e.g., cephalosporins) and anticancer agents.
   Agrochemical Bromination

• Introduces bromine into herbicide/pesticide structures (e.g., bromophenols).

 

3. Polymer & Material Science 

 Flame Retardant Modification

• Brominates polymers (e.g., polystyrene) to enhance flame resistance.
   Photoinitiators

• Used in UV-curable coatings/resins.

 

4. Other Applications

 Gold Extraction

• Oxidizes gold ores in hydrometallurgy.
   Water Treatment

• Disinfectant for pools (slow-release bromine source).

 

Key Properties

• Selectivity: Prefers allylic/benzylic positions over random bromination.

• Solubility: Reacts in DCM, THF, or acetonitrile (insoluble in water).

• Safety: Releases Br2 upon decomposition; handle in fume hood.

Advantages Over Br2

• Controlled reactivity (less hazardous than liquid bromine).

• Solid form (easier to measure/store).

 

Summary

NBS is indispensable for:
 Selective bromination (alkenes, aromatics)
 Pharma/agro intermediates
 Polymer functionalization

Its balance of reactivity and safety makes it a staple in labs, though alternatives like DBDMH are emerging.

 

 

Company Profile

HANGZHOU TIANLONG BIOTECHNOLOGYCO.,LTD
ADD: NO.338, FENGQI EAST ROAD, HANGZHOU CITY, ZHEJANG PROVINCE, CHINA P.C:310020
 
 
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